Health

Potential blood sugar tests use sweat instead of blood

By Dennis Man
Health Day Reporter

Wednesday, June 2, 2021 (HealthDay News) –Measure with new fast, painless sensor Blood sugar Human sweat may mean much less finger stabs for millions of people living with them. Diabetes..

Monitoring your blood glucose to make sure it stays within your target range is Diabetes managementHowever, the pain and inconvenience of daily finger embroidery can be a deterrent for many.

The touch-based test under investigation applies a personalized algorithm that measures sweat blood glucose and correlates it with glucose in the blood. A new proof-of-concept study shows that pre- and post-meal blood glucose predictions are more than 95% accurate.

The new sweat test is not yet ready for prime time, as extensive research is still needed to validate the approach, but diabetic experts not involved in the new study are cautious but optimistic. is.

“Testing for glucose without a needle stick was like the Holy Grail of Diabetes,” said Dr. John Büth, director of the Diabetes Center at the University of North Carolina at Chapel Hill. I hope. ” “These data suggest that there is hope.”

to be continued

Research is ongoing to find alternatives to finger puncture testing to control diabetes and improve the quality of life for people with the disease. The fingers have many sweat glands and sweat a lot, but sweat has lower levels of glucose than blood. In addition, other skin characteristics may cause the readings to vary, resulting in inaccurate blood glucose measurements.

The new sensor contains a polyvinyl alcohol hydrogel that absorbs sweat on a flexible plastic strip. Place your finger on the sensor for 1 minute and the hydrogel will absorb and react to a small amount of sweat and the handheld device will detect a small current.

To ensure that the measurements are accurate, researchers have developed a personalized formula that can measure volunteer blood glucose levels with standard fingertip tests and convert glucose in each person’s sweat to blood glucose levels. .. Diabetics only need to stab their fingers once or twice a month to adjust the device.

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Researchers led by Joseph Wang, a professor of nanotechnology at the University of California, San Diego, said, “This quick and easy touch-based bloodless fingertip sweat glucose assay is significant in improving patient compliance and strengthening diabetes management. Promising.

Their findings were recently published in a journal ACS sensor..

“I think this is an exciting technology and I hope the team can bring it to the finish line.”

Researchers need to investigate the interference of hand-washing soaps, lotions, stains, and sweat-induced blood glucose measurements with food residues.

“Does the commercial version require a special wipe, 3 minutes of sweat buildup, and 1 minute of touch?” Buss asked. It looks a bit too much, but I’m sure some of the 30 million diabetics in the United States prefer it to finger sting. “

What is the conclusion? “There’s a lot to do, but there’s hope,” Buse said.

to be continued

“This technology is innovative and somewhat promising,” agreed Dr. Minisha Sood, an endocrinologist at Lenox Hill Hospital in New York City. “If the algorithm is accurate and scalable, it will be a glucose monitoring game changer.”

Needle-free testing is much more attractive to diabetics. “This is a proof of concept, and it looks like it will be years before we make it a widespread reality,” Sood said.

The authors were funded by the University of California, the Wearable Sensor Center in San Diego, and the Korean National Research Foundation.

For more information

For more information on new diabetes technology American Diabetes Association..

Source: John Buse, MD, Chief of Endocrinology, Director, Diabetes Center, University of North Carolina at Chapel Hill. Minisha Sood, MD, Endocrinologist, Lenox Hill Hospital, New York City. ACS sensor, Online, April 19, 2021

Potential blood sugar tests use sweat instead of blood

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