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Monday, May 7, 2018 (HealthDay News)-Cannabidiol (CBD) oil has become a popular new product in legalized states Medical marijuana..
But experts say there is little evidence for most of these advertised benefits.
To make matters worse, CBD is produced unregulated and the quality of the products varies greatly, says Marcel Bonn-Miller, a part-time assistant professor of psychiatry at the University of Pennsylvania School of Medicine.
“It’s really a wild west,” said Von Miller. “Joe Bob, who started the CBD company, was able to say whatever he wanted to say on the label and sell it to people.”
Cannabidiol is extracted from flowers and buds Marijuana Or hemp plants. It does not cause addiction. The “high” marijuana is caused by the chemical tetrahydrocannabinol (THC).
CBD oil is legal in 30 states where medicinal and / or recreational marijuana is legal. Governance magazine.
According to, 17 additional states have CBD-specific legislation in books Prevention magazine. They are Alabama, Georgia, Indiana, Iowa, Kentucky, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Wisconsin, Wyoming.
Strong evidence for treatment Epilepsy
The only purpose of use of cannabidiol for treatment Epilepsy, There is important scientific evidence to support it.
Last month, the U.S. Food and Drug Administration Advisory Board unanimously recommended approval of the CBD drug Epidiolex to treat two rare forms of childhood. Epilepsy..
Timothy Welty, director of clinical science at Drake University’s Faculty of Pharmaceutical Sciences and Health Sciences, said: In Des Moines, Iowa.
There is too little evidence to draw a firm conclusion on the remaining potential uses of CBD.
This is a potential use of CBD, EpilepsyBut “there is a decent gap between the two,” he said.
The usefulness of CBD as an anti-inflammatory drug is next promising, but experts said their results were primarily obtained from animal studies.
Most other uses are rarely proven
And Welty said that studies involving humans for the use of these other CBDs were either case reports or studies that did not compare results with controls that did not use oil.
“Because there is no control, it’s basically a way to know if we’re dealing with the true effect of the drug, or just the placebo effect. I think someone has been given a beneficial drug. Because, “Welty said.
Experts added that there are also concerns about both the quality of the CBD oil produced and its potential side effects.
Lack of regulation
Due to the legally ambiguous nature of marijuana, the FDA has not intervened to regulate products like CBD oil, Von Miller said. The state is struggling to enforce regulations, but there is no deep federal pocket.
Meanwhile, a 2017 study led by Bonn-Miller found that nearly seven of the ten CBD products did not contain the amount of marijuana extract promised on the label.
According to Von Miller, nearly 43% of products contain too little CBD and about 26% contain too much.
“CBD is a kind of tricky drug because it isn’t well absorbed orally,” Welty explained. “Less than 20 percent of the drug is absorbed orally. If it isn’t made the right way, you may not have many drugs in your systemic circulation.”
To make matters worse, Bonn-Miller and his colleagues found that about one-fifth of CBD products contained intoxicating pot chemical THC.
“If I was a consumer and bought for myself or my kids, I couldn’t trust what was on the label, so I’d like to test to see what’s actually in it.” Bonn-Miller concludes.
Potential interactions with other drugs
Studies on CBD also raised concerns about possible interactions with others. Drug..
This may mean that people taking antiepileptic drugs with CBD may need to lower their doses to avoid side effects, Welty said.
Welty recommends that anyone interested in CBD look for a doctor who has read about the extract and its potential uses.
“My final advice is that people really need to take care of healthcare providers who understand CBD. They need to be monitored and controlled by that individual. That’s the answer. It’s not just about buying CBD because you think it’s going to happen, “Welty said.
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Source: Marcel Bonn-Miller, Ph.D. , University of Pennsylvania School of Medicine, Philadelphia, Part-time Associate Professor of Psychiatry. Timothy Welty, Ph.D., Chairman of the Department of Clinical Sciences, Faculty of Pharmaceutical Sciences and Faculty of Health Sciences, Drake University, Des Moines, Iowa.
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