The jury is still in probiotics

Dennis Thompson
Health Day Reporter

Tuesday, July 17, 2018 (HealthDay News)- Probiotics More and more people are popping capsules containing bacteria to improve intestinal health, making them trendy dietary supplements.

But these are supplement The new review claims that it can harm some patients and researchers are doing insufficient work to track their safety.

Reported side effects are often “missing, inadequate, or inadequate.” Clinical trial Aimed to evaluate the value of Probiotics, According to the survey results released on July 16 Annual report of internal medicine..

In fact, one-third Probiotics French researchers were not provided with any information about the harmful effects.

“I agree that this regulation does not understand the potential harm from the poor medical sector,” he said. Inflammatory bowel disease Program at Lenox Hill Hospital in New York City.

“What’s really appealing isn’t the poor explanation of the harm and the lack of reports, but many researchers in the field thought it was unnecessary,” he said.

person’s Digestive system It contains dozens of trillions of bacteria and we are now learning many subtle ways in which these microscopic insects affect our overall health.

Probiotics According to the American Gastroenterological Association (AGA), it is advertised as a way to improve gut health by introducing healthy bacteria into the system.

Often Probiotics supplement According to AGA, it contains bacteria, but it may also contain other organisms such as yeast.

According to AGA, possible benefits of probiotics include strengthening the immune system, preventing infections, and preventing the spread of harmful bacteria in the intestines.

However, according to the researchers behind the new evidence review, potential harm can result from the use of probiotics, especially for those who are ill or have a weakened immune system. They were headed by Aida Bafeta of the University of Paris 5.

The case reports have linked probiotics to systemic infections in some patients, the researchers said. heart Blood-borne diseases, in particular, occurred after patients took probiotics.

Experts are also concerned that probiotics can harm a person’s metabolism and overstimulate the immune system.

The French team reviewed 384 to see if these potential hazards were being tracked. Clinical trial It aims to test the effectiveness of probiotics, prebiotics, and symbiotics.

Probiotics add bacteria to the human system, while prebiotics are nutrients that promote the growth of intestinal bacteria.Symbiotics is food or Diet supplements Includes both probiotics and prebiotics.

Researchers found that 37% of the trials included in the evidence review did not report safety results. Harm-related data were reported in only 28% of studies.

According to reviews, only one-fifth of clinical trials show the number of serious adverse events that have occurred.

“Some people are aware that probiotics are healthy no matter what,” said Dr. Joshua Novak, an assistant professor of gastroenterology at Mount Sinai School of Medicine in New York City.

These researchers suggest that the results should be reported, Novak continued. “Even if you don’t have it at all, you need to report that,” he said.

Another US expert made an important observation.

“We couldn’t find any evidence to suggest that these products are unsafe,” said French researchers, said Dr. Jeffrey Pridis, an assistant professor at Baylor College of Medicine in Houston.

“Rather, they emphasize the need to report safety data more closely in the future,” Pridez said. “We still generally believe that probiotics, prebiotics, and symbiotics are safe for most people, but these discoveries were made to doctors before starting new microbiota-targeted therapies. We repeat the importance of consulting. “

Tracking potential harm is especially important to protect people with illnesses who are more vulnerable to infection and turning on the immune system, Novak said.

He said he would not recommend probiotics as a first-line treatment for most people Inflammatory bowel disease In most patients.

Novak added that people who eat a healthy diet do not need probiotics.

“The average patient is advised to have a balanced and healthy diet. diet Rich in fruits and vegetables fiber-Abundant food and lean cut It’s protein, “Novak said.fiber It’s a prebiotic, it’s good, and it helps to promote a good microbial flora. “

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Source: Arun Swaminath, MD, Director, Inflammatory Bowel Disease Program, Lenox Hill Hospital, New York City. Joshua Novak, MD, Associate Professor, Medicine and Gastroenterology, Mount Sinai School of Medicine, New York City. Geoffrey Preidis, MD, Ph.D. , Associate Professor, Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston; Annual report of internal medicine, July 16, 2018

The jury is still in probiotics

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