Saline spray may slow the spread of COVID in the lungs: Study

Friday, September 24, 2021 (HealthDay News)

Aqueous salt solution may help to stop SARS-Brazilian researchers report that the CoV-2 virus has been tracked.

However, while saline may prevent viral replication, it does not provide complete protection or cure for infection. COVID-19 (New Coronavirus Infection)..

“This is not a single solution and should be used in the first few days after infection,” said Christian Guzzo, a professor of microbiology at the Institute of Biomedical Sciences at the University of São Paulo.

In this study, 1.1% sodium chloride saline reduced viral replication by 88%. In testing infected lung cells In the laboratory.

“Reducing viral replication means reducing the severity of the disease and the inflammatory response. COVID-19 (New Coronavirus Infection) Is a complex disease consisting of a viral replication stage that can be treated with hypertonic saline and a much wider range of systemic inflammation. This second phase is intense and can cause many complications in a variety of organs, “Guzzo explained in a news release from the São Paulo Research Foundation.

If the strategy proves to be effective Clinical trial, Researchers said it could lead to the development of new methods for prevention or treatment COVID-19 (New Coronavirus Infection)..

“Given the seriousness of the pandemic, we believe it is important to extend this research line by implementing it. Clinical trial It is designed to test the effectiveness of using a spray … it helps prevent the virus from spreading into infected organisms and reduces the likelihood of more severe inflammation, “Gutso added. ..

“It’s very simple and cheap,” Guzzo said. “It has already been used prophylactically against other respiratory illnesses and COVID-19 (New Coronavirus Infection) By reducing the viral load. “

She suggested that it could be added to the safety protocol without replacing the use of face masks, social distance and vaccination.

“If its effectiveness is confirmed in clinical trials, it could reduce viral replication in the nose and throat,” Guzzo said.

Researchers suggest that saline can be tested in two ways. One is nasal drops, such as those found in pharmacies. It can be used by front-line healthcare professionals and other people who are highly exposed to the virus.

Another method is to inhale or spray saline. lung, More complicated.

The findings were recently published online in the journal ACS Pharmacology & Translational Science..

For more information

National Institutes of Health Details of COVID-19..

Source: Sao Paulo Research Foundation, News Release, September 21, 2021

Stephen Reinberg

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Saline spray may slow the spread of COVID in the lungs: Study

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