Scientists have made their discoveries using advanced whole-genome sequencing technology.Their results were published online in the journal on September 14th. Nature genetics..
The Sardinia study, launched in 2001, is a partnership with the National Laboratory of the United States. aging, Institute of Genetics and Biomedical Sciences, Italian Research Council and University of Michigan, Ann Arbor. The purpose of this study is to identify genes associated with diseases and other traits.
Initially, the study examined about 2.5 million common genetic variations. However, advances in sequencing technology have allowed researchers to analyze the association of more than 17 million genetic mutations with a variety of health problems.
Scientists have found that the two genetic mutations have a significant impact on the height of the people of Sardinia, an island off the coast of Italy in the Mediterranean Sea. Combining these variations can reduce the height by 2.3 inches. The authors of the study found that many of the genes associated with traits and disease risk in this population may be important in larger and more diverse groups because Sardinians are genetically more interrelated. I pointed out.
Two more new gene variants related to blood Lipid Levels were also identified along with five new mutants associated with indicators of blood inflammation.Researchers paid attention to both Lipid Levels and inflammation affect risk Heart disease..
Finally, researchers also analyzed gene regulation hemoglobin, A protein that carries oxygen in the blood. They found 23 associations at 10 different gene positions.Researchers pointed out its lowness hemoglobin Levels can cause life-threatening illnesses such as Sickle cell anemia..
-Mary Elizabeth Dallas
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Source: National Institute on Aging, News Release, September 14, 2015
Researchers identify genes associated with height and heart disease
Source link Researchers identify genes associated with height and heart disease