Infant antibiotics may increase the risk of childhood obesity

Alan Moses
Health Day Reporter

Thursday, November 1, 2018 (HealthDay News)-New studies suggest that babies prescribed antibiotics before the age of two are more likely to become obese children.

The relationship was not very strong, but drugs for acid reflux may also increase the risk.

The findings track the medication history and incidence of childhood obesity in hundreds of thousands of children up to the age of eight. All were treated through the US military health care system.

As to why the association was found, researchers argue that such drugs may be related to the effects of such drugs on the delicate microbiome found in the intestines of growing children. I attached it.

“We did not assess the microbiome status of these children,” stressed research author Dr. Cade Nirund, Lieutenant Colonel of the US Air Force. “And because this was an observational study, we can only show relevant findings, not specific causes.

“Therefore, we speculate that this is related to the changes in the child’s microbiome caused by these drugs,” he added. “But it could just be the result of an infection, or you might have a fever with or without antibiotics, or it might be related to the psychosocial dynamics of your family. No. We don’t know yet. “

Regarding what parents should do with these discoveries, Nylund says that the most important thing is to ensure that children take the medicines they need, but not when it is not justified. Told.

For example, Nylund states that acid reflux disease treatments, such as histamine blockers and proton pump inhibitors, are often prescribed to infants when not indicated. With regurgitation medicine. And most babies grow out of problems by 12 months. “

On the other hand, Nylund said, “Antibiotics play a major role in the treatment of infectious diseases and always do so.

“And I’m sure parents would hate not treating their children with antibiotics because of infections because of concerns about obesity,” he added.

The study will be published in the journal on November 1st. Intestines, Researchers tracked approximately 333,000 children born between 2006 and 2013.

Over 241,000 people were prescribed antibiotics by the age of two. Nearly 40,000 people were prescribed histamine blockers and more than 11,000 were prescribed proton pump inhibitors. About 6,000 children were prescribed all three medications.

Based on an average of four pediatrician visits between the ages of two and eight, researchers determined that nearly 47,000 children (14 percent) became obese. Of these, about 9,600 had never been prescribed antibiotics or acid reflux disease medications during infancy. I had the rest.

After accumulating medication history for the incidence of obesity, the research team concluded that infants prescribed antibiotics had a 26% increased risk of childhood obesity by the age of three. In multiple antibiotic classes.

Drugs for acid reflux also appeared to increase the risk of childhood obesity, but the relationship was characterized as “weak.”

Dr. Luci Gupta, a senior scientist in pediatric health research at Northwestern University’s Fineberg School of Medicine in Chicago, said: “Antibiotics that can alter the gut flora and affect other health conditions. The findings are interesting because they raise questions about factors such as drugs. ” .. She wasn’t involved in the study.

However, Gupta warned that, for now, the findings should only be considered as “significant associations.” “A true understanding of causes and consequences will require further research because of the complexities affected by many environmental, behavioral and genetic factors,” she said.

Copyright © 2018 Health Day. all rights reserved.


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Sources: Cade Nylund, MD, MS, Lieutenant Colonel, U.S. Air Force, Medical Corps, and Associate Professor, Pediatrics, Uniformed Services University, University of the Health Sciences, Bethesda, MD; Ruchi Gupta, MD, MPH, Senior Scientist, Children’s Health Research and Professor, Pediatrics and Medicine, Northwestern University of Finebergs School of Medicine, Chicago. November 1, 2018, Intestines,online

Infant antibiotics may increase the risk of childhood obesity

Source link Infant antibiotics may increase the risk of childhood obesity

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