If your kidneys fail, you may be at increased risk of dementia

Friday, May 7, 2021 (HealthDay News)

Chronic Kidney disease Risk may increase dementia, According to a Swedish study.

For chronic people Kidney disease, Bean-shaped organs gradually lose their ability to filter waste products from the blood and eliminate water.

“Even a slight decrease in renal function is associated with an increased risk. Cardiovascular disease There is increasing evidence of a relationship between the kidneys and the brain. ” Dr. Hong Xu, a postdoctoral fellow at the Karolinska Institute in Stockholm, said.

For this study, her team analyzed the health data of about 330,000 elderly people in Stockholm.No one had dementia Or had a kidney transplant Dialysis When the research started.

6% were diagnosed during an average of 5 years of follow-up dementia.. When renal function declines, dementia Increased, researchers have found.

Fees dementia According to the authors of the study, patients with kidney filtration below 30 mL / min were more than four times higher than those with normal filtration of 90-104 mL.

After other adjustments dementia Risk factors (etc. smoking, alcohol use, High blood pressure And Diabetes), The researchers concluded that people with a filtration rate of 30-59 mL per minute had a 71% higher risk of dementia than those with normal renal function. People with a filtration rate of less than 30 mL had a 162% higher risk.

The researchers also analyzed blood test data from approximately 206,000 study participants who underwent multiple blood tests per year to estimate the rate of decline in renal function.

Faster reductions in kidney filtration rates were also associated with a higher risk of dementia diagnosis, according to a study published online May 5 in the journal. Neurology..

The researchers said that 10% of cases of dementia in this study could be due to renal filtration rates of 60 mL / min or less. This is because the proportion of cases of dementia is higher than that due to other risk factors such as: Heart disease And Diabetes..

Xu pointed out that, like chronic kidney disease, the risk of dementia increases with age.

“It’s important to identify correctable risk factors because there is no effective treatment to delay or prevent dementia,” she said in a journal news release. “If we can prevent or delay some cases of dementia by preventing or treating kidney disease, it can bring significant public health benefits.”

The study links renal function to the development of dementia, but does not prove the cause and effect, Xu added.

About 15% of adults in the United States have chronic kidney disease.

For more information

The National Kidney Foundation Chronic kidney disease..

Source: Neurology, News Release, May 5, 2021

Robert Prite

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The sole purpose of the kidneys is to filter the blood.
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If your kidneys fail, you may be at increased risk of dementia

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