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Genes associated with hypertension found in African Americans

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Monday, September 16 (HealthDay News)-African Americans are likely to develop High blood pressure Larger new studies, than whites, and now, have identified four common genetic mutations that affect their risk.

The study, which involves about 30,000 African Americans in 19 locations across the United States, is the largest study to find out how genes affect them. blood pressure According to researchers, in blacks.

Researchers point out that most gene discoveries so far have been made in whites, and in previous studies in blacks, blood pressure..

Genes account for 40% to 50% of human risk High blood pressure (((High blood pressure). The four genetic variations identified in this study also affect other racial / ethnic groups, the researchers said.Other risk factors High blood pressure Including lifestyle, diet When obesity..

This study also confirmed the role of other genes in increasing risk High blood pressure..

“In addition to their disproportionate suffering, High blood pressure Xiaofeng Zhu, a professor of epidemiology and biostatistics at Case Western Reserve University, said in a university news release that “African Americans are early in life compared to other ancestral individuals. It occurs in. Therefore, it is important to study. This population has a better understanding of genetic susceptibility. High blood pressure.. “

Survey results recently published American Journal of Human Genetics..

“It is unclear how genes regulate blood pressure, but our findings contribute to a better understanding of blood pressure pathways that may lead to the development of future drug discovery targets. High blood pressure It may lead to a cure for clinical treatment. “

Brendan Keating, a geneticist and co-lead author of research at the Center for Applied Genomics at the Philadelphia Children’s Hospital, said: Scientists close to biological pathways and may suggest useful targets for new therapies. Keating also Pediatrics At the University of Pennsylvania.

–Robert Preidt

MedicalNews
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References

Source: Case Western Reserve University, News Release, September 10, 2013

Genes associated with hypertension found in African Americans

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