Antibodies to early strains of COVID may not fight new mutants: study

Wednesday, September 22, 2021 (HealthDay News)

Current antibody COVID-19 (New Coronavirus Infection) vaccination Studies have found that it does not bind well to new variants of the virus.

Researchers, from previously published treatises, vaccination.. They focused on antibodies against peplomer, which is part of the virus that binds to and infects receptors in human cells.It’s the most target vaccination..

“Antibody reactions are very relevant to everything from understanding natural infections to how to recover from them. vaccination Design. ” In a news release at the University of Illinois at Urbana-Champaign, senior researcher Nicolas Wu said he was a professor of biochemistry.

The body can make an estimated 1 trillion kinds of antibodies, so if people are making similar antibodies against a particular virus, it is vaccination It can be designed to pull it out. It also means that it is likely to improve responsiveness to it, Wu explained.

The study found that many antibodies converged into two groups, demonstrating an immune response to the virus.

Timothy Tan, the lead author of the graduate student, said:

He said mutations were less of an issue before the study began. But Tan added that when they emerged, researchers wanted to see if common antibodies could bind to new mutants.

“This antibody response is very common with the original strain, but it doesn’t actually interact with the mutant,” Wu said. “Of course, it raises concerns that the virus will evolve and escape the body’s major antibody reactions. Some antibodies should still be effective-the body is an antibody against many parts of the virus, not just the spike protein. -The group of antibodies seen in this particular study is not very effective. “

The researchers said they would like to do similar research on antibody responses to deltas and other mutants to see if they also provoke reactions and how they differ from the original strain.

The findings were recently published in the journal Nature Communications..

For more information

Centers for Disease Control and Prevention and Prevention Have more information about COVID-19 vaccine..

Source: University of Illinois at Urbana-Champaign, News Release, September 17, 2021

Stephen Reinberg

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Antibodies to early strains of COVID may not fight new mutants: study

Source link Antibodies to early strains of COVID may not fight new mutants: study

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